Agitated nutsche filter dryer factory today: The CSTR reactor offers several advantages compared to traditional open systems. The design of a CSTR reactor allows for efficient and homogenous mixing, leading to quicker reaction times and improved product uniformity. The continuous stirring offered by the CSTR reactor requires less energy to achieve homogeneity than traditional open systems, helping decrease operational costs. The closed-system design of a CSTR reactor offers superior safety compared to other reactors due to the reduced chance of hazardous reactions occurring outside the system. By allowing for higher pressures and temperature control, CSTR reactors can yield greater amounts of product with fewer impurities than other systems. See extra info on CSTR Reactor.
In the production process of AIPs, in order to reduce the material loss and avoid environment pollution that may be caused by the material transfer after crystallization, the subsequent filtration, washing and drying processes of the material are usually completed in one single piece of equipment, which is called Three-in-One; for short or Agitated Nutsche Filter Dryer(ANFD). The most common Three-in-One used in drug production is with flat bottom, and there is no doubt that it has advantages in the production of sterile APIs, however, certain defects in another side as well, including small filter area in the circular flat bottom, side discharge (there is always material left behind), poor drying performance, small movement of material during the drying process, and low efficient heat transfer, more limits of drying, etc.
The complete drive unit includes a drive system and dispersed motors for the stirring arm and spiral, installed on the top of the equipment and at the center of the top cover, easy to maintain and replace, which is one of the standard specifications of Wuxi Zhanghua ‘s single-cone mixer and dryer. The modular construction of seals and bearing boxes, as well as the robust construction of the drive and rotary arms, are quite reliable and reduce downtime. These verified technologies have been successfully applied to many installation cases. Each design has its own unique features, advantages, and a wide range of applications.
The mixer operates by rotating the V-shaped container on its axis. The rotation causes the materials to move in a complex motion, which includes rolling, cascading, and crossing over each other. As a result, the materials are constantly being intermixed and distributed evenly throughout the container. V type blenders are known for their versatility and ability to handle a wide range of materials, including powders, granules, pastes, and viscous liquids. They are particularly effective at blending materials with different particle sizes and densities. The mixing process can be further enhanced by incorporating additional features such as intensifier bars or choppers to break up agglomerates or lumps.
The agitated nutsche filter component of this equipment allows for efficient solid-liquid separation. The slurry or liquid mixture is introduced into the vessel, and the agitator stirs, mixes, or agitates the contents. This agitation enhances the filtration process by promoting the separation of solids from the liquid phase. The liquid passes through the filter medium, while the solids form a cake on top of it. Once the filtration process is complete, the filter dryer component comes into play. The retained filter cake is subjected to drying operations to remove moisture and achieve the desired level of dryness. Various methods can be employed, such as applying heat, vacuum, or a combination of both. The integrated drying capability of the filter dryer ensures efficient evaporation of moisture from the filter cake.
Wuxi Zhanghua Pharmaceutical Equipment Co.,Ltd was founded in 1976, committed to researching, developing and manufacturing reaction, crystallization, filtration, drying equipment. With the development of the leading technologies for more than 40 years, our engineering equipment is not only for the pharmaceutical industry, but also for fine chemicals, pesticides, new energy, new materials and other industries. We customize the integrated solution of reaction, crystallization, filtration and drying process equipment for clients. See extra details at https://www.filter-dryer.com/.
Zhanghua is a renowned manufacturer of world-class pharmaceutical equipment, including high-quality stainless steel reaction kettles. Our reactor tanks are designed and engineered to meet the most demanding industrial requirements, offering exceptional performance, reliability, and durability. Our stainless steel reactors are made from premium-grade materials that offer superior resistance to corrosion, abrasion, and other forms of wear and tear. They feature a robust construction that can withstand extreme temperatures and pressures, making them ideal for a wide range of applications in the chemical, pharmaceutical, and food industries.
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